SPICA 2024

19th International Symposium on Preparative and Industrial Chromatography and Allied Techniques

 Milan, Italy    October 15-18, 2024

Programme


13:00

Registration & SPICA Hackathon kick-off session

Optional Workshops (subject to prior registration)

14:00

Start of parallel sessions

Workshop 1
Workshop 2
Workshop 3
Workshop 1
14:00
Fundamentals of Chromatography
Prof. Giorgio CARTA
UNIVERSITY OF VIRGINIA, Charlottesville, United States
Workshop 2
14:00
Viral Vectors
Dr Michael SCHULTE
MERCK KGAA, Darmstadt, Germany
Dr Mattia SPONCHIONI
POLITECNICO DI MILANO, Milano, Italy
Workshop 3
14:00
Continuous Chromatography for Small Molecules
Dr Olivier DAPREMONT
SK PHARMTECO, Rancho Cordova, United States
15:30

Coffee Break

16:00

Start of parallel sessions

Workshop 4
Workshop 5
Workshop 6
Workshop 4
16:00
Digitalization of Biopharmaceutical Processes
Prof. Massimo MORBIDELLI
ARISTOTLE UNIVERSITY OF THESSALONIKI, Thessaloniki, Greece
Workshop 5
16:00
mRNA, pDNA and Oligos
Dr Alessandro BUTTE
DATAHOW, Zurich, Switzerland
Workshop 6
16:00
Continuous Bio-Chromatography
Dr Mattia SPONCHIONI
POLITECNICO DI MILANO, Milano, Italy
17:30

End of Workshop Sessions

SPICA 2024 Opening Ceremony

17:45

Opening Address

Prof. Massimo MORBIDELLI
ARISTOTLE UNIVERSITY OF THESSALONIKI, Thessaloniki, Greece
Dr Mattia SPONCHIONI
POLITECNICO DI MILANO, Milano, Italy
17:55

Opening Keynote Lecture
Integration of Biology and Engineering to Enable Industrialization of Complex Biotherapeutics

Dr Konstantin B. KONSTANTINOV
RING THERAPEUTICS, Cambridge, United States
18:35

Welcome Reception

19:35

End of the Day

20:15

Informal and optional gathering at Mercato Centrale

07:30

Registration

Session 1 - Sustainability

08:15

Introduction

08:20

Water Conservation and Recycling Strategies in Bioprocessing: The Role of Chromatography

Prof. Alois JUNGBAUER
UNIVERSITY OF NATURAL RESOURCES AND LIFE SCIENCES, Vienna, Austria
08:50

A Process Systems Engineering Perspective for the Design and Assessment of Integrated Monoclonal Antibody Production Processes

Dr Sara BADR
UNIVERSITY OF TOKYO, Tokyo, Japan
09:10

Oral Communication 1

09:30

Oral Communication 2

09:50

Coffee break & Exhibition

Session 2 - Stationary Phases and Membranes

10:20

Introduction

10:25

Innovative Axial Flow Membrane Module for Protein Chromatography

Prof. Cristiana BOI
ALMA MATER STUDIORUM-UNIVERSITÀ DI BOLOGNA, Bologna, Italy
10:55

Purification of Nucleic Acids by Ionic-liquids-based Ligands: Exploiting a Multimodal Behavior

Dr Fani SOUSA
UNIVERSITY OF BEIRA INTERIOR, Covilhã, Portugal
11:15

Oral Communication 3

11:35

Oral Communication 4

11:55

Lunch break & Exhibition

13:00

SPICA Hackathon Working Groups

13:00

Optional Vendor Seminars

Session 3 - Small Molecules

14:00

Introduction

14:05

Is MultiColumn Continuous Chromatography still Used to Support New Drug R&D?

Dr Antoni SEVERINO
UCB, Braine-l'Alleud, Belgium
14:35

Pros and Cons on the Use of Dimethyl Carbonate as a Green Alternative to Acetonitrile in Reversed Phase Liquid Chromatography for Analytical and Preparative Purposes

Prof. Martina CATANI
UNIVERSITÀ DEGLI STUDI DI FERRARA, Ferrara, Italy
14:55

Oral Communication 5

15:15

Oral Communication 6

15:35

Coffee break & Exhibition

SPICA Slam Session

16:05

10 Slam Presentations by young scientists

Poster Session 1

17:50

Presentation of posters with odd numbers & networking

19:00

End of the Day

Session 5 - Proteins and Peptides

08:15

Introduction

08:20

A Roadmap to Fast and in-silico DSP Process Development: Applied Modelling Concept Utilization

Dr Dejan ARZENSEK
NOVARTIS, Ljubljana, Slovenia
08:50

How to Design an Automated Low-cost Pilot Scale Magnetic Bioseparation Process for Protein Separation from Complex Mixtures

Prof. Sonja BERENSMEIER
TECHNICAL UNIVERSITY OF MUNICH, Munich, Germany
09:10

Oral Communication 7

09:30

Oral Communication 8

09:50

Coffee break & Exhibition

Session 6 - New Modalities

10:20

Introduction

10:25

(R)Evolution in Downstream Processing of New Modalities: What Will be the Role of Chromatography?

Dr Cristina PEIXOTO
IBET, Oeiras, Portugal
10:55

Digital Twin and Process Analytical Technologies Application to Vaccine Purification Process Development

Dr Antonio CARDILLO
GLAXOSMITHKLINE, Siena, Italy
11:15

Oral Communication 9

11:35

Oral Communication 10

11:55

Lunch break & Exhibition

13:00

SPICA Hackathon Working Groups

13:00

Optional Vendor Seminars

Session 7 - Continuous Chromatography

14:00

Introduction

14:05

Large-scale TIDES purification with MCSGP under GMP

Dr Ralf EISENHUTH
BACHEM AG, Bubendorf, Switzerland
14:35

Extending the Range of Twin-Column Chromatography (MCSGP): Dynamic Control and Process Concepts

Dr Thomas MÜLLER-SPÄTH
CHROMACON AG, Zurich, Switzerland
14:55

Oral Communication 11

15:15

Oral Communication 12

15:35

Coffee break & Exhibition

Session 8 - Digitalization

16:05

Introduction

16:10

Digitalization of DSP Operations and the Role of Hybrid Models

Dr Alessandro BUTTE
DATAHOW, Zurich, Switzerland
16:40

Harnessing Explainable Machine Learning in Image Analysis and Large Pre-trained Neural Networks to Predict and Analyse Process Performance in Biomanufacturing

Dr Lukas GERSTWEILER
THE UNIVERSITY OF ADELAIDE, Adelaide, Australia
17:00

Oral Communication 13

17:20

Oral Communication 14

Poster Session 2

17:40

Presentation of posters with even numbers & networking

18:55

End of the Day

20:30

SPICA Conference Dinner at i Chiostri di San Barnaba

Session 9 - Modeling and Control

09:00

Introduction

09:05

Digital Tools for Informed Design of Chromatographic Separation Processes

Dr Maria PAPATHANASIOU
IMPERIAL COLLEGE LONDON, London, United Kingdom
09:35

Biopharma 4.0 for Biologics Manufacturing Under Pandemic Constraints - Digital Twins in Quality-by-Design Based Process Design and Control for Autonomous Operation

Prof. Jochen STRUBE
CLAUSTHAL UNIVERSITY OF TECHNOLOGY, Clausthal-Zellerfeld, Germany
09:55

Oral Communication 15

10:15

Oral Communication 16

10:35

Coffee break & Exhibition

SPICA Award Session

11:05

Introduction

11:10

SPICA Tube - best video presentations

11:30

SPICA Slam winner presentation

11:45

SPICA Hackathon group presentation

12:15

Poster Prizes

12:30

SPICA 2024 Closing Remarks